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Sleep regularity is a stronger predictor of mortality risk than sleep duration (2023)

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Article URL: https://academic.oup.com/sleep/article/47/1/zsad253/7280269

Comments URL: https://news.ycombinator.com/item?id=48919363

Points: 572

# Comments: 283

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574 points · 284 comments · 查看原帖

  1. petilon

    Magnesium supplementation solved my sleep issues. I have seen many doctors, including sleep specialists, regarding insomnia. They all pointed to one source as the reason for the sleep issues: stress. And they all wanted to put me on prescription sleeping pills. I said no to that. Sleeping pills can cause dependence, and they often treat the symptom rather than the underlying cause. As a software developer, I am used to finding and fixing the underlying problem instead of relying on the quick fixes these doctors were offering me. After much research, I figured out what I believe was the underlying problem, and the fix for it. The underlying problem was magnesium deficiency. As a software developer, I spend much of the day doing mentally demanding work. This is the kind of stress the doctors were talking about. Stress can increase the body's demand for magnesium and may contribute to low m

  2. A1kmm

    I wonder how much of this is driven by confounding variables they haven't accounted for. They do factor in shift work as a categorical variable, and employment status as a categorical variable not taking into account occupation. But probably occupation (not a variable here) interacts with sleep status. Any job that involves a lot of flying (pilot, crew, people travelling for business) get more cosmic radiation exposure, for example, and potentially more sleep disruption. Certain operations and manufacturing jobs correlated with exposure to carcinogens also likely correlate with less regular sleep, possibly in a way that isn't corrected for by the limited shift work categories.

  3. nottorp

    I wonder how many of these "surprising" results are markers of other life style decisions. Regular sleeping hours as a marker for a less stressful life? Also ran across this: https://pmc.ncbi.nlm.nih.gov/articles/PMC5105607/ I doubt it's the actual reading. Maybe having a calmer life where you take the time to relax with a book.

  4. djoldman

    As always with a lot of these: it's not saying causation. You might measure the speed of your car by putting your hand out of the window and notice that the wind force on your hand is strong when the car goes fast. Putting your hand out of the window and then blocking the wind with a book doesn't make the car slow down. Keyword: "associated" EDIT: I meant to communicate that it doesn't make the car slow down as much as your hand behind and blocked by the book (feeling almost no wind), would imply.

  5. ssgodderidge

    Couldn’t this effect be classic cause vs correlation? Perhaps someone who has a consistent schedule is hypothetically more likely to make healthier choices on average?

  6. timbaboon

    Largest medical insurance company (Discovery Health) in South Africa has just launched a sleep rewards program as part of their wellness program (Vitality). The idea is that you get rewarded for getting good sleeping scores... which is not entirely in your control, but anyway. Their model is built by looking at years of sleep data combined with health insurance claims. They place a large emphasis on sleep regularity. Anyway, just interesting to see this study come up and it seems to match up sort of with the Vitality stuff. There will ofc be many confounding variables though...

  7. redanddead

    Just my 2c Bryan Johnson says you should base your life around your sleep. He’s totally right … but he won’t get young men to sleep in at 8pm New sleep meds are creating a new lever here and serve a real empowering function in a way that culture hasn’t caught up to yet When we think of traditional sleep meds we think of sedatives and it has an identity connotation to it. The new meds coming out, not just in sleep either, are changing a lot of things. I’m talking about designer drugs, new pathways, multiple agonists etc etc. By total accident a month ago, I was prescribed a medication for sleep, lemborexant (not into trade names for drugs, more power to generics) I didn’t plan on ever getting a sleep med. I don’t see myself as a sleep med guy lol. I didn’t walk into a clinic thinking I’d ever want one either. But to me this feels like a peptide or an athletic recovery supplement. And I th

  8. keeda

    Somewhat related, I once met the author of a book about sleep [1] and asked about my specific case. At that time I was splitting half my time across two continents 10 time zones apart but working largely in the same timezone, about 2 - 3 months at a time. That is, every 2 - 3 months I switched from a 1st shift sleep schedule to a "2.5th shift" one. So I asked him how bad that was for my health. He said that as long as people are mostly regular in their sleep hours, the actual timings don't matter much. However, extended periods of irregular sleep schedules are actually (his words) "classified as a type of carcinogen." I briefly looked into the evidence at the time but did not find it very concerning. TFA does make a more compelling case by linking it to all-cause mortality. [1] I believe it was The Sleep Solution by M. Chris Winter, though I may be wrong. I can only remember it had a blu